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BioNike's Defence Tolerance Extreme is the brand's most cushioned cream for skin that reacts to everything — 21-ingredient INCI, fragrance-free, nickel-tested per batch. Beta-glucan + panthenol + bisabolol + allantoin = real soothing trifecta, plus shea butter, squalane, and vitamin E. The cream Italian dermatologists prescribe for clients post-laser or with cosmetic intolerance.
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In-clinic and at-home treatments that use the same active ingredients.
The 14–28 day structured protocol for resetting a compromised skin barrier — strip the routine to the studs (cleanser, ceramide cream, SPF), drop every active, let the skin rebuild itself.
The gentlest exfoliation there is — pineapple or papaya enzymes that digest dead skin without acid irritation.
The most aggressive skin-resurfacing laser in dermatology — two weeks of recovery in exchange for collagen, tone, and texture results that nothing else comes close to.
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Defence Tolerance Extreme Cream by BioNike is formulated for sensitive, dry, normal skin. BioNike's Defence Tolerance Extreme is the brand's most cushioned cream for skin that reacts to everything — 21-ingredient INCI, fragrance-free, nickel-tested per batch. Beta-glucan + panthenol + bisabolol + allantoin = real soothing trifecta, plus shea butter, squalane, and vitamin E. The cream Italian dermatologists prescribe for clients post-laser or with cosmetic intolerance.
The key active ingredients in Defence Tolerance Extreme Cream are Panthenol, Beta-Glucan, Shea Butter, Vitamin E (Tocopherol). It's known for: 21-ingredient minimalist fragrance-free INCI and beta-glucan is a documented soothing/barrier active.
Yes, Defence Tolerance Extreme Cream targets sensitivity, redness, dryness. 21-ingredient minimalist fragrance-free INCI
Defence Tolerance Extreme Cream retails for around $33, which places it in the mid range for moisturizers. Check the "Where to Buy" section above for current retailer prices.
The main drawbacks to be aware of: dimethicone present (silicone-avoiders skip); rich texture not for combination/oily; limited international distribution outside Italy.
A suggested daily routine featuring this product, with complementary picks.
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Vegan Kombucha Tea Essence
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Defence Hydractive Intensive Moisturising Serum
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Defence Tolerance Extreme Cream
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Defence Tolerance Extreme Cream
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