At Homeexfoliation
Enzyme Peel
Medically reviewed by ChokChok · Updated April 17, 2026
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The gentlest exfoliation there is — pineapple or papaya enzymes that digest dead skin without acid irritation.
How It Works
Proteolytic enzymes selectively digest the peptide bonds in dead skin cells (corneocytes) without affecting living cells — a literal, molecular form of exfoliation. No pH shift, no stinging, no increased sun sensitivity. Best for skin too sensitive for AHAs but still wanting the post-exfoliation glow.
What to Expect
A powder-to-paste or cream applied for 5–10 minutes, rinsed. Skin looks immediately brighter and feels smoother; no tingle or sting. Weekly cadence is plenty.
Deep Dive
Enzyme peels use proteolytic enzymes — bromelain (from pineapple), papain (from papaya), or pumpkin enzymes — to selectively break down the keratin bonds that hold dead skin cells together. Unlike AHAs and BHAs, enzymes work only on dead proteinaceous material and don't alter the skin's pH or trigger irritation. The at-home versions are powders (Tatcha Rice Enzyme Powder, Dermalogica Daily Microfoliant, The Ordinary Pumpkin Enzyme Mask) activated with water into a paste. Clinic versions are stronger formulations used by estheticians as a pre-treatment for facials.
Pros
- ✓ gentlest exfoliation available
- ✓ works on sensitive + rosacea-prone skin
- ✓ no sun sensitivity
- ✓ immediate brightening
Cons
- ✗ milder than AHAs — less dramatic results
- ✗ less useful on thick congestion
- ✗ enzyme stability is tricky (powder format is best)
Risks & Side Effects
- ⚠ enzyme allergies (rare)
- ⚠ over-exfoliation if combined with acids same day
- ⚠ irritation if left on too long
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This is not medical advice. Always consult your healthcare provider or dermatologist before trying new treatments, especially in-clinic procedures.
Routines for Related Concerns
Step-by-step K-beauty routines that complement Enzyme Peel.
Products That Complement Enzyme Peel
Products featuring the same key active ingredients — great for extending results between treatments.
Related Reading
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Frequently Asked Questions
How often should I do Enzyme Peel?
weekly or 2x weekly. Most people see results within immediate.
Does Enzyme Peel hurt?
The pain level for Enzyme Peel is none. Downtime: none.
What are the risks of Enzyme Peel?
The main risks and side effects to be aware of: enzyme allergies (rare); over-exfoliation if combined with acids same day; irritation if left on too long. Always consult a qualified provider, especially for in-clinic procedures.
How much does Enzyme Peel cost?
Enzyme Peel is in the budget-friendly range. Typical cost: $15-60 per product.
Who is Enzyme Peel best for?
Enzyme Peel works best for sensitive, dry, normal, rosacea-prone skin, particularly those concerned with dullness, sensitivity, dryness. It may not be ideal for acne-prone, severe-fungal-acne skin.
