Biologique Recherche vs Payot â side by side, no bias.
Our pick
Crème Iso-Placenta
9/10 ¡ Biologique Recherche
| Crème Iso-Placenta | Crème N°2 Nuit | |
|---|---|---|
| Brand | Biologique Recherche | Payot |
| Category | moisturizer | moisturizer |
| Editor Rating | 9/10 â | 8/10 |
| Category | moisturizer | moisturizer |
| Texture | Rich regenerating cream | Rich cream |
| Finish | Plumped, smoothed, restored | Calming |
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| Verdict | Biologique Recherche's regenerating cream â named for the plant-based 'placental' polypeptide complex that gives the formulation its restorative character. (To be clear: there's no animal placenta â the active is a hydrolyzed vegetable protein complex modelled on the growth-factor signature of placental tissue.) The active stack pairs the polypeptide complex with two synthetic peptides (Acetyl Tetrapeptide-2 and Palmitoyl Tripeptide-1) for collagen-support, panthenol and allantoin for tissue repair, centella asiatica extract for soothing, hyaluronic acid and squalane for hydration and lipid restoration. The cream is BR's go-to for skin in active recovery â post-procedure, post-illness, or just chronically depleted by stress. At $145 for 50ml, luxury-tier pricing, but the formulation depth is genuinely difficult to match. | Payot's night cream â a Parisian spa-grade moisturiser with the facial-massage methodology baked in. |
