Comparison
Crème Iso-Placenta vs Cicaplast Hand Cream
Biologique Recherche vs La Roche-Posay — side by side, no bias.

Biologique Recherche
Crème Iso-Placenta
9/10moisturizer

La Roche-Posay
Cicaplast Hand Cream
8.1/10moisturizer
Our pick
Crème Iso-Placenta
9/10 · Biologique Recherche
| Crème Iso-Placenta | Cicaplast Hand Cream | |
|---|---|---|
| Brand | Biologique Recherche | La Roche-Posay |
| Category | moisturizer | moisturizer |
| Editor Rating | 9/10 ★ | 8.1/10 |
| Category | moisturizer | moisturizer |
| Texture | Rich regenerating cream | Rich cream |
| Finish | Plumped, smoothed, restored | Restored |
| Skin Types | ||
| Targets | ||
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| Verdict | Biologique Recherche's regenerating cream — named for the plant-based 'placental' polypeptide complex that gives the formulation its restorative character. (To be clear: there's no animal placenta — the active is a hydrolyzed vegetable protein complex modelled on the growth-factor signature of placental tissue.) The active stack pairs the polypeptide complex with two synthetic peptides (Acetyl Tetrapeptide-2 and Palmitoyl Tripeptide-1) for collagen-support, panthenol and allantoin for tissue repair, centella asiatica extract for soothing, hyaluronic acid and squalane for hydration and lipid restoration. The cream is BR's go-to for skin in active recovery — post-procedure, post-illness, or just chronically depleted by stress. At $145 for 50ml, luxury-tier pricing, but the formulation depth is genuinely difficult to match. | LRP's hand-care expression of the Cicaplast formula — panthenol + madecassoside + shea butter + thermal water. The hand cream that French pharmacy customers pair with the Cicaplast Baume B5 as a complete repair regimen. |