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CeraVe Itch Relief is the rare drugstore lotion that pairs an actual OTC active — 1% pramoxine hydrochloride, an FDA-approved topical anesthetic in use since 1953 — with the brand's signature ceramide barrier complex. Where most 'soothing' lotions stop at glycerin and panthenol, this one numbs the itch directly while ceramides NP, AP, and EOP plus phytosphingosine and cholesterol rebuild the lipid layer that's failing in the first place. Niacinamide handles inflammation, allantoin and Tasmannian pepperberry reinforce the calming brief, and zinc citrate adds gentle antimicrobial support. It's marketed for body use (bug bites, sunburn, eczema flares) but works on face for genuinely itchy, compromised skin where a regular moisturizer isn't pulling its weight. The pramoxine kicks in within minutes — that's the difference between this and a normal CeraVe lotion, which takes hours of barrier rebuild before you feel relief. Use during active flares, then step down to CeraVe Moisturizing Cream for maintenance. At ~$14, it's the cheapest OTC anti-itch product that actually treats the underlying barrier issue.
Allantoin
4/5 evidence
Calms redness and irritation, Promotes wound healing
Ceramides
5/5 evidence
barrier repair, moisture retention
Glycerin
5/5 evidence
Pulls water into the top layers of skin, Restores and supports the skin barrier
Hyaluronic Acid
4/5 evidence
hydration, plumping
Niacinamide
5/5 evidence
brightening, pore minimizing
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Itch Relief Moisturizing Lotion by CeraVe is formulated for dry, sensitive, normal skin. CeraVe Itch Relief is the rare drugstore lotion that pairs an actual OTC active — 1% pramoxine hydrochloride, an FDA-approved topical anesthetic in use since 1953 — with the brand's signature ceramide barrier complex. Where most 'soothing' lotions stop at glycerin and panthenol, this one numbs the itch directly while ceramides NP, AP, and EOP plus phytosphingosine and cholesterol rebuild the lipid layer that's failing in the first place. Niacinamide handles inflammation, allantoin and Tasmannian pepperberry reinforce the calming brief, and zinc citrate adds gentle antimicrobial support. It's marketed for body use (bug bites, sunburn, eczema flares) but works on face for genuinely itchy, compromised skin where a regular moisturizer isn't pulling its weight. The pramoxine kicks in within minutes — that's the difference between this and a normal CeraVe lotion, which takes hours of barrier rebuild before you feel relief. Use during active flares, then step down to CeraVe Moisturizing Cream for maintenance. At ~$14, it's the cheapest OTC anti-itch product that actually treats the underlying barrier issue.
The key active ingredients in Itch Relief Moisturizing Lotion are Allantoin, Ceramides, Glycerin, Hyaluronic Acid, Niacinamide. It's known for: 1% pramoxine hydrochloride is a clinically-proven topical anesthetic — relief within minutes and Three ceramides + phytosphingosine + cholesterol rebuild barrier alongside symptom relief.
Yes, Itch Relief Moisturizing Lotion targets sensitivity, dryness, redness. 1% pramoxine hydrochloride is a clinically-proven topical anesthetic — relief within minutes
Itch Relief Moisturizing Lotion retails for around $14, which places it in the budget range for moisturizers. Check the "Where to Buy" section above for current retailer prices.
The main drawbacks to be aware of: Contains alcohol denat. low in the formula — fine for most but worth flagging for very reactive skin; Pramoxine is short-acting — works fast but needs reapplication every few hours; Body-lotion texture and bottle size are oversized for face-only use.
A suggested daily routine featuring this product, with complementary picks.
Hydrating Facial Cleanser
CeraVe · cleanser
Hydrating Toner for Face
CeraVe · toner
Hydrating Hyaluronic Acid Serum
CeraVe · serum
Skin Renewing Vitamin C Serum
CeraVe · serum
Itch Relief Moisturizing Lotion
CeraVe · moisturizer
Hydrating Sunscreen Face Lotion SPF 30
CeraVe · sunscreen
Itch Relief Moisturizing Lotion
CeraVe · moisturizer
