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VT bundles the two biggest 2026 buzzwords — PDRN and exosomes — onto a calming cica base, and somehow lands a serum that actually feels like all three are doing the work.
Centella Asiatica
4/5 evidence
soothing, wound healing
Ceramides
5/5 evidence
barrier repair, moisture retention
Peptides
3/5 evidence
anti-aging, collagen support
Exosomes
3/5 evidence
cell-to-cell signaling, regeneration support
PDRN / Polynucleotides
4/5 evidence
stimulates fibroblast activity, supports collagen renewal
Other routine steps with complementary ingredients.
Side-by-side ingredient breakdowns vs. the closest alternatives.
In-clinic and at-home treatments that use the same active ingredients.
The Korean cosmetic-derm treatment that injects polynucleotides derived from salmon sperm DNA to stimulate collagen and tissue repair. Yes, really.
An in-clinic facial built around topically applied stem-cell exosomes (often combined with microneedling or laser) — the post-procedure recovery protocol marketed as a stand-alone treatment.
The four-night rotation that turned Dr. Whitney Bowe into a TikTok celebrity and actually lowered retinoid purge for millions.
Guide
PDRN and PN are both salmon-DNA-derived ingredients used in skincare and aesthetics — but they're not the same thing. We break down the molecular difference, the in-clinic vs topical applications, and which to pick for which goal.
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Guide
PDRN is polydeoxyribonucleotide — DNA fragments derived from salmon sperm, injected or applied topically to stimulate collagen and tissue repair. We break down what the science actually supports, which products are worth it, and why Rejuran is everywhere.
Read more →
Guide
Exosomes are 2026's most-hyped skincare ingredient. We explain what they actually are, the difference between stem-cell-derived and plant-based versions, the in-clinic vs retail distinction, and whether the hype matches the science.
Read more →
PDRN Cica Exosome Ampoule by VT Cosmetics is formulated for normal, sensitive, mature, combination skin. VT bundles the two biggest 2026 buzzwords — PDRN and exosomes — onto a calming cica base, and somehow lands a serum that actually feels like all three are doing the work.
The key active ingredients in PDRN Cica Exosome Ampoule are Centella Asiatica, Ceramides, Peptides, Exosomes, PDRN / Polynucleotides. It's known for: PDRN + exosomes + cica trio with real evidence behind each and strengthens barrier instead of pushing past it.
Yes, PDRN Cica Exosome Ampoule targets fine lines, redness, dullness, sensitivity. PDRN + exosomes + cica trio with real evidence behind each
PDRN Cica Exosome Ampoule retails for around $32, which places it in the mid range for serums. Check the "Where to Buy" section above for current retailer prices.
The main drawbacks to be aware of: exosome category is still science-young — long-term data is light; more expensive than VT's entry-tier serums.
A suggested daily routine featuring this product, with complementary picks.
CICA Mild Foam Cleanser
VT Cosmetics · cleanser
CICA Skin Toner
VT Cosmetics · toner
PDRN 100 Essence
VT Cosmetics · essence
PDRN Cica Exosome Ampoule
VT Cosmetics · serum
CICA Cream
VT Cosmetics · moisturizer
Anthelios UVMune 400 Invisible Fluid SPF50+
La Roche-Posay · sunscreen
CICA Cream
VT Cosmetics · moisturizer
