ISDIN vs MartiDerm — side by side, no bias.
Our pick
Isdinceutics Retinal Intense
9/10 · ISDIN
| Isdinceutics Retinal Intense | The Originals Night Renew Ampoules | |
|---|---|---|
| Brand | ISDIN | MartiDerm |
| Category | serum | serum |
| Editor Rating | 9/10 ★ | 8.3/10 |
| Category | serum | serum |
| Texture | Concentrated serum | Single-dose ampoule |
| Finish | Smooth, absorbed | Smoothed, resurfaced |
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| Verdict | ISDIN's retinaldehyde powerhouse — a step above retinol in the vitamin A hierarchy. Retinal (retinaldehyde) converts to retinoic acid in one step instead of two, meaning faster results with less irritation than prescription tretinoin. ISDIN pairs it with HPR (hydroxypinacolone retinoate) for a dual-retinoid approach, plus bakuchiol as a botanical synergist and hyaluronic acid for hydration. The Spanish derm brand's most serious anti-aging product. | MartiDerm's nighttime retinol ampoules in The Originals line — encapsulated retinol + peptides in single-dose format. The Spanish ampoule format applied to retinol, eliminating the air-exposure stability issue that plagues retinol bottles. |
