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Mesoestetic's at-home counterpart to the Cosmelan in-clinic depigmenting peel — and the most-prescribed melasma maintenance cream in global dermatology. The Cosmelan method is a two-step protocol: an in-clinic mask applied by an aesthetic physician, then 6-9 months of at-home Cosmelan 2 cream to maintain and extend the depigmenting effect. The maintenance cream's active stack is dense — azelaic acid, kojic acid, phytic acid, ascorbyl glucoside, retinyl palmitate, niacinamide, and arbutin all work in parallel through different melanin-synthesis pathways. The result is a cumulative, multi-month depigmenting protocol that can rival in-clinic results when used as directed. At $130 for 30g, premium pricing — but Cosmelan 2 alone (without the in-clinic peel) still delivers meaningful results for stubborn melasma that other OTC products can't move.
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Cosmelan 2 Maintenance Cream by Mesoestetic is formulated for normal, combination, mature skin. Mesoestetic's at-home counterpart to the Cosmelan in-clinic depigmenting peel — and the most-prescribed melasma maintenance cream in global dermatology. The Cosmelan method is a two-step protocol: an in-clinic mask applied by an aesthetic physician, then 6-9 months of at-home Cosmelan 2 cream to maintain and extend the depigmenting effect. The maintenance cream's active stack is dense — azelaic acid, kojic acid, phytic acid, ascorbyl glucoside, retinyl palmitate, niacinamide, and arbutin all work in parallel through different melanin-synthesis pathways. The result is a cumulative, multi-month depigmenting protocol that can rival in-clinic results when used as directed. At $130 for 30g, premium pricing — but Cosmelan 2 alone (without the in-clinic peel) still delivers meaningful results for stubborn melasma that other OTC products can't move.
The key active ingredients in Cosmelan 2 Maintenance Cream are Azelaic Acid, Kojic Acid, Retinol. It's known for: multi-pathway depigmenting stack: azelaic + kojic + phytic + arbutin + retinyl palmitate and world's most-prescribed professional depigmenting protocol.
Yes, Cosmelan 2 Maintenance Cream targets hyperpigmentation, fine lines. multi-pathway depigmenting stack: azelaic + kojic + phytic + arbutin + retinyl palmitate
Cosmelan 2 Maintenance Cream retails for around $130, which places it in the premium range for moisturizers. Check the "Where to Buy" section above for current retailer prices.
The main drawbacks to be aware of: $130 for 30g is genuinely premium tier; best results require pairing with the in-clinic Cosmelan mask (sold separately); retinyl palmitate is photo-sensitising — strict daily SPF required.
A suggested daily routine featuring this product, with complementary picks.
