MartiDerm vs Sesderma — side by side, no bias.
Our pick
Pigment Zero DSP-Bright Ampoules
8.8/10 · MartiDerm
| Pigment Zero DSP-Bright Ampoules | Reti Age Anti-aging Serum | |
|---|---|---|
| Brand | MartiDerm | Sesderma |
| Category | serum | serum |
| Editor Rating | 8.8/10 ★ | 8.5/10 |
| Category | serum | serum |
| Texture | Lightweight ampoule serum | Lightweight dropper serum |
| Finish | Brightening | Smooth, refined, renewed |
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| Verdict | Martiderm's Pigment Zero DSP-Bright stacks five depigmenting mechanisms in one ampoule formula: tranexamic acid (gold-standard melasma drug), hexylresorcinol (Synovea HR — the potent tyrosinase inhibitor), ascorbyl glucoside (stable vitamin C), niacinamide (melanin transfer inhibitor), and Bellis Perennis (daisy flower extract — alpha-MSH antagonist). €72 for genuinely uncommon five-pathway pigmentation work. | Sesderma's retinol serum — and the reason Spanish dermatologists keep recommending this brand for patients who want prescription-adjacent results without the prescription. The formulation delivers retinol through Sesderma's proprietary liposomal technology (nanosome encapsulation), which the brand has been refining for two decades. The liposomal delivery system serves two purposes: it stabilizes the retinol against oxidation (extending shelf life and potency) and it enhances penetration depth (delivering retinol below the stratum corneum where it can influence fibroblast activity). Hyaluronic acid provides hydration support to offset retinol's drying tendency. At ~$48 for 30ml, it competes directly with SkinCeuticals Retinol 0.3 and Medik8 Crystal Retinal — at roughly half the price. The liposomal encapsulation also means reduced surface irritation compared to free-form retinol at equivalent concentrations. PM use only; sunscreen the next morning is mandatory. |
