Comparison
Isdinceutics Melaclear Serum vs Isdinceutics Retinal Intense
ISDIN vs ISDIN โ side by side, no bias.
ISDIN vs ISDIN โ side by side, no bias.

ISDIN
Our pick
Isdinceutics Retinal Intense
9/10 ยท ISDIN
| Isdinceutics Melaclear Serum | Isdinceutics Retinal Intense | |
|---|---|---|
| Brand | ISDIN | ISDIN |
| Category | serum | serum |
| Editor Rating | 8.4/10 | 9/10 โ |
| Category | serum | serum |
| Texture | Lightweight serum | Concentrated serum |
| Finish | Brightened | Smooth, absorbed |
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| Targets | ||
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| Verdict | ISDIN's targeted depigmentation serum in the Isdinceutics line โ tranexamic acid + glycolic + SAP + niacinamide. Designed for melasma and stubborn pigmentation, with the multi-mechanism stack that Spanish pharmacy excels at. โฌ58 premium positioning matches Mesoestetic Tran3x. | ISDIN's retinaldehyde powerhouse โ a step above retinol in the vitamin A hierarchy. Retinal (retinaldehyde) converts to retinoic acid in one step instead of two, meaning faster results with less irritation than prescription tretinoin. ISDIN pairs it with HPR (hydroxypinacolone retinoate) for a dual-retinoid approach, plus bakuchiol as a botanical synergist and hyaluronic acid for hydration. The Spanish derm brand's most serious anti-aging product. |