Ask ChokChok AI
Get instant answers about Priority B (22% Niacinamide)
Try asking
Where to Buy
We’re still tracking retailers for this one. In the meantime:
Get instant answers about Priority B (22% Niacinamide)
Try asking
We’re still tracking retailers for this one. In the meantime:
Step 4: Treatment
Targeted actives — serums, ampoules, and treatments for specific concerns.
Synergie Skin's higher-concentration Priority B pushes niacinamide to 22% — one of the highest concentrations available outside professional-clinical channels. The product is positioned for oily, combination, acne-prone, and sebum-overactive skin types where the maximum niacinamide concentration can deliver measurable pore-and-oil-control benefits. Zinc PCA is added at this tier for additional sebum regulation. The expected use protocol is graduation from the standard Vitamin B (13%) to Priority B (22%) once the lower concentration is well-tolerated and the user wants stronger action.
Other routine steps with complementary ingredients.
Side-by-side ingredient breakdowns vs. the closest alternatives.
In-clinic and at-home treatments that use the same active ingredients.

The four-night rotation that turned Dr. Whitney Bowe into a TikTok celebrity and actually lowered retinoid purge for millions.

The 60-minute California salon-chain facial — Dermalogica-trained technician, face-mapping diagnostic, targeted actives, and Face Fitness massage.

Korea's most popular clinic facial — a multi-step machine treatment that simultaneously exfoliates, extracts, and infuses skin with customized serums using a patented vortex technology.
Guide
Biologique Recherche's Lotion P50 is the most polarizing product in French beauty — a multi-acid exfoliant that smells terrible, costs €70+, and has a waitlist at certain spas. We decode the formulation, the versions, the correct usage, and whether the cult reputation matches the clinical reality.
Read more →
Guide
Spain has the deepest eye-cream bench in global beauty. We rank twelve eye treatments from Mesoestetic, ISDIN, Endocare, Natura Bissé, Sesderma, MartiDerm, Bella Aurora, Xhekpon, and BABÉ — from €8 pharmacy legends to €180 spa-grade formulas.
Read more →
Guide
Brazil's pharmacy skincare ecosystem rivals France's — but the brands are largely unknown outside Latin America. Adcos, Mantecorp Skincare, Episol, Ada Tina, Theraskin, and Pink Cheeks together form a dermatologist-channel ecosystem with depth in sunscreens, melasma protocols, and cosmeceutical actives that France's pharmacy giants don't match. Here's the brand-by-brand guide and why the next decade will see Brazilian pharmacy go global.
Read more →
Priority B (22% Niacinamide) by Synergie Skin is formulated for oily, combination, acne-prone skin. Synergie Skin's higher-concentration Priority B pushes niacinamide to 22% — one of the highest concentrations available outside professional-clinical channels. The product is positioned for oily, combination, acne-prone, and sebum-overactive skin types where the maximum niacinamide concentration can deliver measurable pore-and-oil-control benefits. Zinc PCA is added at this tier for additional sebum regulation. The expected use protocol is graduation from the standard Vitamin B (13%) to Priority B (22%) once the lower concentration is well-tolerated and the user wants stronger action.
The key active ingredients in Priority B (22% Niacinamide) are Niacinamide, Panthenol. It's known for: 22% niacinamide is genuinely at the high-end of cosmeceutical formulations — this is unusual ingredient density and Zinc PCA addition adds direct sebum-regulating action beyond niacinamide alone.
Yes, Priority B (22% Niacinamide) targets pores, oiliness, hyperpigmentation, acne. 22% niacinamide is genuinely at the high-end of cosmeceutical formulations — this is unusual ingredient density
Priority B (22% Niacinamide) retails for around $130, which places it in the premium range for serums. Check the "Where to Buy" section above for current retailer prices.
The main drawbacks to be aware of: premium pricing (~AU$190+); 22% concentration definitely too aggressive for sensitive skin — start with 13% Vitamin B first; fragrance components present — patch-test essential.
A suggested daily routine featuring this product, with complementary picks.
Ultime8 Sublime Beauty Cleansing Oil
Shu Uemura · cleanser
Gokujyun Premium Hyaluronic Acid Lotion
Hada Labo · toner
Vegan Kombucha Tea Essence
Dr. Ceuracle · essence
Priority B (22% Niacinamide)
Synergie Skin · serum
Ceramide Ato Concentrate Cream
Illiyoon · moisturizer
Anthelios UVMune 400 Invisible Fluid SPF50+
La Roche-Posay · sunscreen
Ceramide Ato Concentrate Cream
Illiyoon · moisturizer