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The world's first wrinkle treatment to receive MHLW (Japanese FDA) approval specifically for wrinkle improvement — a big deal in Japan. Niacinamide at pharmaceutically-approved concentration + peptides. Target it: nasolabial folds, crow's feet, glabellar lines. Expect results at 12+ weeks.
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Side-by-side ingredient breakdowns vs. the closest alternatives.
In-clinic and at-home treatments that use the same active ingredients.
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Wrinkle Shot Medical Serum by POLA is formulated for mature, dry, normal, combination skin. The world's first wrinkle treatment to receive MHLW (Japanese FDA) approval specifically for wrinkle improvement — a big deal in Japan. Niacinamide at pharmaceutically-approved concentration + peptides. Target it: nasolabial folds, crow's feet, glabellar lines. Expect results at 12+ weeks.
The key active ingredients in Wrinkle Shot Medical Serum are Niacinamide, Peptides. It's known for: Japan's first MHLW-approved wrinkle serum and Niacinamide at approved concentration.
Yes, Wrinkle Shot Medical Serum targets fine lines. Japan's first MHLW-approved wrinkle serum
Wrinkle Shot Medical Serum retails for around $185, which places it in the premium range for serums. Check the "Where to Buy" section above for current retailer prices.
The main drawbacks to be aware of: Expensive and slow-acting; Fragranced; Results are real but subtle.
A suggested daily routine featuring this product, with complementary picks.
Ultime8 Sublime Beauty Cleansing Oil
Shu Uemura · cleanser
B.A Lotion
POLA · toner
Vegan Kombucha Tea Essence
Dr. Ceuracle · essence
Wrinkle Shot Medical Serum
POLA · serum
B.A The Cream
POLA · moisturizer
Anthelios UVMune 400 Invisible Fluid SPF50+
La Roche-Posay · sunscreen
B.A The Cream
POLA · moisturizer
