Peter Thomas Roth vs SkinMedica — side by side, no bias.
Our pick
TNS Advanced+ Serum
9/10 · SkinMedica
| Potent-C Power Serum | TNS Advanced+ Serum | |
|---|---|---|
| Brand | Peter Thomas Roth | SkinMedica |
| Category | serum | serum |
| Editor Rating | 8.8/10 | 9/10 ★ |
| Category | serum | serum |
| Texture | Lightweight oil-serum | Thick peach-pink serum |
| Finish | Smooth, brightened, glowing | Silky smoothing |
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| Verdict | PTR's vitamin C hero — 20% THD ascorbate (the oil-soluble, ultra-stable form of vitamin C) with ferulic acid and vitamin E in an oil-serum that doesn't tingle, doesn't oxidize, and doesn't require pH balancing. This is the alternative for those who want SkinCeuticals C E Ferulic-level potency without the L-ascorbic temperament (oxidation, irritation, pH sensitivity). The price is closer to SkinCeuticals than to The Ordinary — but the formulation is genuinely the gold standard for stable vitamin C. Best for mature skin chasing brightening + collagen support. | The US cosmetic-derm world's post-procedure gold standard. TNS — Tissue Nutrient Solution, a growth-factor complex derived from human fibroblast conditioned media — paired with signal peptides and barrier support. Clinical data on photoaging is published and serious. $295 is genuinely expensive, but the 4–6 week post-Fraxel case is exactly what this product was built for. |
