MartiDerm vs Sesderma — side by side, no bias.
Our pick
Pigment Zero DSP-Bright Ampoules
8.8/10 · MartiDerm
| Pigment Zero DSP-Bright Ampoules | Azelac Ru Liposomal Serum | |
|---|---|---|
| Brand | MartiDerm | Sesderma |
| Category | serum | serum |
| Editor Rating | 8.8/10 ★ | 8.6/10 |
| Category | serum | serum |
| Texture | Lightweight ampoule serum | Watery liposomal serum |
| Finish | Brightening | Calmed, brightened, smoothed |
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| Verdict | Martiderm's Pigment Zero DSP-Bright stacks five depigmenting mechanisms in one ampoule formula: tranexamic acid (gold-standard melasma drug), hexylresorcinol (Synovea HR — the potent tyrosinase inhibitor), ascorbyl glucoside (stable vitamin C), niacinamide (melanin transfer inhibitor), and Bellis Perennis (daisy flower extract — alpha-MSH antagonist). €72 for genuinely uncommon five-pathway pigmentation work. | Sesderma's anti-pigmentation hero — and Spanish dermatologists' favorite alternative to hydroquinone for melasma, post-acne marks, and rosacea-related hyperpigmentation. The active stack pairs azelaic acid (the gentle-but-effective tyrosinase inhibitor and anti-inflammatory) with diacetyl boldine ('RU', a Boldea boldus-derived brightener) and niacinamide for sebum regulation and tone-evening, plus a low dose of glycolic acid for gentle resurfacing. All carried in liposomal phosphatidylcholine for deeper delivery without irritation — meaningful for the rosacea and sensitive-skin users that traditional pigmentation actives often can't tolerate. At $60 for 30ml, premium pricing — but the multi-active stack and the rosacea-friendly profile make it competitive with much more expensive prescription alternatives. |
