ISDIN vs Mesoestetic — side by side, no bias.
Our pick
Glycolic + E + F Ampoules
8.6/10 · Mesoestetic
| Isdinceutics Night Peel | Glycolic + E + F Ampoules | |
|---|---|---|
| Brand | ISDIN | Mesoestetic |
| Category | exfoliant | exfoliant |
| Editor Rating | 8.5/10 | 8.6/10 ★ |
| Category | exfoliant | exfoliant |
| Texture | Watery liquid in single-dose ampoules — apply and leave on overnight | Lightweight ampoule |
| Finish | Invisible — absorbs fully, no residue | Resurfaced |
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| Verdict | ISDIN Night Peel is the product that proves the ampoule format works as brilliantly for exfoliation as it does for antioxidants. Each sealed glass ampoule contains a precise dose of multi-acid exfoliant — glycolic acid (AHA for surface-cell turnover), malic acid (gentler AHA for sensitive-skin compatibility), tartaric acid (antioxidant AHA from grape), and citric acid (pH-adjusting, mild exfoliant) — buffered with glycerin, sodium lactate, and saccharide isomerate (a biomimetic moisturiser that binds to the skin's surface for hours). The ampoule format solves the stability problem that plagues AHA products in open bottles: each dose is factory-sealed, never exposed to air or light, and delivers the acids at their intended concentration and pH every single time. No oxidation. No degradation. No guessing whether the product still works three months after opening. The instructions are simple: snap the ampoule, apply to clean face, sleep. The acids work overnight at a controlled pace — not fast enough to irritate, fast enough to smooth texture, even tone, refine pores, and reduce fine lines over 4-6 weeks of consistent use. This is pharmaceutical-grade resurfacing delivered in a format invented by a Barcelona pharmacy. The 10-ampoule box is a 10-night treatment course. The results accumulate. The ritual is addictive. | Mesoestetic's Glycolic + E + F Ampoules deliver a 10% glycolic acid at-home peel in single-use ampoule format, paired with vitamin E (tocopheryl acetate + tocopherol) and Vitamin F (linoleic acid + squalane) for the buffer. The ampoule format prevents oxidation and prevents over-application. €85 for a clinic-grade weekly ritual. |
