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ISDIN's night recovery serum — and one of the most innovative formulations in Spanish dermocosmetics. The star ingredient is melatonin, used here not as a sleep aid but as a topical antioxidant: melatonin is a potent free-radical scavenger that neutralizes oxidative damage accumulated during daytime UV exposure. Layered with bakuchiol (plant-based retinol alternative — same receptor activation, less irritation), stabilized vitamin C (ascorbyl glucoside), and HPR (hydroxypinacolone retinoate — a next-gen retinoid that binds directly to retinoid receptors without conversion). The three-in-one night recovery concept (antioxidant repair via melatonin + retinoid renewal via bakuchiol/HPR + brightening via vitamin C) is clinically elegant. At ~$65 for 30ml, mid-premium pricing that's justified by the ingredient innovation. The night serum ISDIN's dermatologist network uses as a retinol-sensitive alternative.
Other routine steps with complementary ingredients.
Side-by-side ingredient breakdowns vs. the closest alternatives.
In-clinic and at-home treatments that use the same active ingredients.
A 24-karat-gold-plated microchannel device that delivers custom serum cocktails — usually micro-doses of Botox, hyaluronic acid, vitamins, and peptides — into the upper dermis.
Microneedling's gentler, no-downtime sister — a silicone-tip cartridge oscillating at ~150,000 vibrations/min that pushes serums into the epidermis without piercing the skin.
A cocktail of vitamins, amino acids, and hyaluronic acid injected into the superficial dermis — French-born, globally adopted, endlessly remixed.
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Isdinceutics Melatonik by ISDIN is formulated for normal, combination, dry, mature skin. ISDIN's night recovery serum — and one of the most innovative formulations in Spanish dermocosmetics. The star ingredient is melatonin, used here not as a sleep aid but as a topical antioxidant: melatonin is a potent free-radical scavenger that neutralizes oxidative damage accumulated during daytime UV exposure. Layered with bakuchiol (plant-based retinol alternative — same receptor activation, less irritation), stabilized vitamin C (ascorbyl glucoside), and HPR (hydroxypinacolone retinoate — a next-gen retinoid that binds directly to retinoid receptors without conversion). The three-in-one night recovery concept (antioxidant repair via melatonin + retinoid renewal via bakuchiol/HPR + brightening via vitamin C) is clinically elegant. At ~$65 for 30ml, mid-premium pricing that's justified by the ingredient innovation. The night serum ISDIN's dermatologist network uses as a retinol-sensitive alternative.
The key active ingredients in Isdinceutics Melatonik are Bakuchiol, Vitamin C, Vitamin E (Tocopherol). It's known for: topical melatonin is a genuinely innovative antioxidant — potent free-radical scavenging and bakuchiol + HPR deliver retinoid benefits without classic retinol irritation.
Yes, Isdinceutics Melatonik targets fine lines, dullness, hyperpigmentation. topical melatonin is a genuinely innovative antioxidant — potent free-radical scavenging
Isdinceutics Melatonik retails for around $65, which places it in the premium range for serums. Check the "Where to Buy" section above for current retailer prices.
The main drawbacks to be aware of: $65 for 30ml is mid-premium — comparable Korean products cost less; melatonin in skincare is innovative but the clinical evidence base is still growing; dimethicone-based formula may not suit silicone-averse consumers.
A suggested daily routine featuring this product, with complementary picks.
Isdinceutics Essential Cleansing
ISDIN · cleanser
Gokujyun Premium Hyaluronic Acid Lotion
Hada Labo · toner
Vegan Kombucha Tea Essence
Dr. Ceuracle · essence
Isdinceutics Melatonik
ISDIN · serum
Isdinceutics Age Contour Night
ISDIN · moisturizer
Eryfotona Actinica SPF 50+
ISDIN · sunscreen
Isdinceutics Age Contour Night
ISDIN · moisturizer
