
Singuladerm
Targeted Spanish dermocosmetics built around single hero molecules โ one concern, one Xpert, sold only through pharmacies.
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Singuladerm is the Spanish pharmacy indie that built its catalogue around a single naming convention: every product is an Xpert + one concern. Xpert Drone (vitamin C), Xpert Lift (retinol), Xpert Acne (salicylic + niacinamide), Xpert Brightening (tranexamic acid). Founded in 2014 by Madrid pharmacist Susana Fos Anguera and a pharmacy collective, the brand sells exclusively through Spanish farmacias โ no department stores, no big retail, no Sephora. The result is a quietly cult-favorite range among Spanish dermatologists for value-priced retinol and depigmenting serums that compete on formulation depth, not on marketing. Behind every farmacia counter in Spain you'll find Singuladerm sitting next to ISDIN, Sesderma, and Martiderm โ and pharmacists prescribe it by concern.
Strengths
- + pharmacy-only distribution = pharmacist-vetted credibility
- + Xpert + concern naming maps cleanly to skincare goals
- + well-dosed single-active formulas (15% L-ascorbic in Xpert Drone)
- + value pricing relative to Sesderma and ISDIN equivalents
Weaknesses
- โ Spanish-pharmacy distribution makes international sourcing hard
- โ INCI lists contain phenoxyethanol + parfum across most formulas
- โ single-active focus means fewer all-in-one cream options
- โ brand identity is more functional than aspirational
The Singuladerm Story
Singuladerm was founded in Madrid in 2014 by pharmacist Susana Fos Anguera together with a Spanish pharmacy collective. The thesis was specifically anti-prestige: build dermocosmetics for the Spanish farmacia channel exclusively, refuse department-store distribution to keep prices honest, and let pharmacists prescribe by concern rather than by brand. The Xpert range was designed around single hero molecules โ each product earns its place by addressing one specific concern with one well-dosed active. Xpert Drone leads with 15% L-ascorbic acid + ferulic acid; Xpert Lift uses retinol + bakuchiol synergy; Xpert Acne combines salicylic acid with niacinamide and tea tree; Xpert Brightening stacks tranexamic acid, alpha-arbutin, and phytic acid. The brand is now stocked in pharmacies across Spain and select EU markets, has a small DTC presence at singuladerm.es, and continues to refuse the Sephora-tier distribution that would force pricing inflation. The brand identity is unmistakably pharmacy: white packaging, restrained typography, and concern-led product names.
All Singuladerm Products
4 products reviewed and rated.

Xpert Lift Retinol Serum
Singuladerm's Xpert Lift pairs retinol with bakuchiol โ the now-classic anti-aging combination that lets you get retinol benefits with reduced irritation. Retinol + bakuchiol + vitamin E + sodium hyaluronate is a tight, well-thought-out stack. โฌ45 for retinol + bakuchiol synergy is substantially cheaper than international alternatives.

Xpert Youth
Singuladerm's hero global anti-aging serum from the Xpert Youth line โ Argireline + Matrixyl Synthe'6 + niacinamide + multi-weight HA in a concentrated treatment serum. The brand's anchor anti-aging product.
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