
Rejuran
Clinical PDRN skincare from the company that pioneered salmon-DNA aesthetics — lab-grade regeneration for everyone.
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Rejuran is the consumer-skincare arm of Pharma Research Products, the Korean biopharma company that developed the original Rejuran Healer injectable — the same PDRN (polydeoxyribonucleotide) dermal treatment that's been a staple of Korean aesthetic clinics since 2014. The topical line translates that clinical DNA into daily-use products, anchored by the patented c-PDRN® complex at 0.5% concentration plus proprietary DOT® (Dermal Optimizing Technology) delivery. The Turnover Ampoule is the hero: a lightweight serum that targets fine lines, firmness, and texture with the same salmon-DNA active that made the injectable famous. Rejuran launched at Sephora US in 2024, won the 2025 Olive Young Slow Aging award, and has become the face of the PDRN trend that's dominating K-beauty in 2025–2026. The price point is premium-mid ($45–55), justified by the clinical pedigree and patented delivery system. Worth reaching for if you want the PDRN trend from the company that actually invented it.
Strengths
- + invented the PDRN category — the original, not a copycat
- + patented c-PDRN® and DOT® delivery backed by published clinical data
- + available at Sephora US, Olive Young Global, Amazon
- + fragrance-free, cruelty-free, paraben-free across the line
Weaknesses
- − premium-mid pricing ($45–55) in a space filling with budget PDRN alternatives
- − small SKU count — focused but limited range
- − the salmon-DNA story can feel gimmicky until you read the papers
- − injectable brand heritage may confuse consumers expecting instant clinical results from topicals
The Rejuran Story
Rejuran started in 2014 as a clinical aesthetic brand under Pharma Research Products, a Korean biopharma company specializing in regenerative medicine. The original Rejuran Healer injectable — a PDRN (polydeoxyribonucleotide) skin booster derived from salmon DNA — became one of the most popular dermal treatments in Korean clinics, known for improving skin texture, elasticity, and hydration at the cellular level. In 2019, the company launched the topical consumer line, translating its proprietary c-PDRN® complex into daily-use serums, creams, and masks using DOT® (Dermal Optimizing Technology) for enhanced penetration. The Turnover Ampoule became the breakout hero, earning Olive Young Awards recognition and landing at Sephora US in 2024. The brand's clinical pedigree — actual pharmaceutical research, not marketing-grade 'science' — sets it apart in the increasingly crowded PDRN space. Manufactured in Korea under pharmaceutical-grade standards.
All Rejuran Products
3 products reviewed and rated.

Turnover Ampoule c-PDRN 0.5%
The ampoule that started the salmon-DNA craze — and still the gold standard in the PDRN space. Rejuran's patented c-PDRN® at 0.5% concentration is the topical version of the injectable Rejuran Healer that Korean aesthetic clinics have used since 2014 for skin regeneration. The DOT® delivery technology enhances penetration of the polynucleotide fragments into the dermis, where they stimulate fibroblast activity, boost collagen synthesis, and improve cellular turnover. The result is measurably firmer, smoother, more luminous skin over 4-8 weeks — the kind of gradual-but-real improvement that doesn't come from hype ingredients. At $52 it's premium for K-beauty but a fraction of the $300+ injectable treatment it's derived from. Available at Sephora US.

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