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The "baby skin" injection — a Korean-developed injectable made from polynucleotides (DNA from salmon sperm) that repairs skin at a cellular level, improving elasticity, hydration, and texture from within.
Rejuran contains Polydeoxyribonucleotide (PDRN), derived from salmon DNA that is structurally similar to human DNA. When injected intradermally, PDRN acts as a cell growth stimulator — it binds to adenosine receptors which activates wound healing pathways, stimulates fibroblast activity, and increases production of collagen, elastin, and hyaluronic acid. It essentially "wakes up" dormant skin repair mechanisms. The results compound with multiple sessions.
Treatment takes 30–45 minutes. Topical numbing cream is applied 30–45 minutes beforehand. The injections are made via a micro-needling technique (multiple micro-injections) or a mesotherapy gun across the entire face. You will experience mild to moderate pain (4–6/10) during the procedure. Immediately after: significant swelling and papules at injection sites (looks alarming — completely normal). These resolve within 24–48 hours. Avoid makeup, exercise, and saunas for 24 hours.
Rejuran (리쥬란) was developed by Pharmaresearch Korea and launched in South Korea around 2014. It quickly became one of the most sought-after treatments in Korean dermatology clinics, earning the nickname "아기피부 (baby skin) injection" due to its skin texture-improving effects. The treatment is now available globally but remains most affordable and prevalent in Korea (₩100,000–300,000 per session). Clinical studies from Korean universities show significant improvement in skin elasticity and hydration biomarkers.
Pregnancy Safety
Avoid during pregnancy
This is not medical advice. Always consult your healthcare provider or dermatologist before trying new treatments, especially in-clinic procedures.
Step-by-step K-beauty routines that complement Rejuran Healer (PDRN Injection).
Initial course: 3–4 sessions, 2–4 weeks apart. Maintenance: every 3–6 months. Most people see results within 2–4 weeks after first session; full effect after completing initial course.
The pain level for Rejuran Healer (PDRN Injection) is moderate. Downtime: 24–48 hours swelling and papules.
Rejuran Healer (PDRN Injection) should be avoided during pregnancy. Consult your healthcare provider about safer alternatives.
The main risks and side effects to be aware of: Bruising and swelling post-treatment (expected); Rare: infection, allergic reaction; Not suitable for those with fish allergies. Always consult a qualified provider, especially for in-clinic procedures.
Rejuran Healer (PDRN Injection) is in the premium range. Typical cost: $150–400 per session.