Brand Comparison
Biotherm vs Rejuran
A head-to-head comparison of two popular K-beauty brands. Which one is right for your skin?
Our Pick
Rejuran
Higher editor rating (8.7 vs 7.5)
Biotherm
The French pharmacy brand most people forget exists. Life Plankton Essence is a legitimate hero serum that's been consistently reformulated since 1952. Aquasource gel moisturizer is a classic. L'Oréal ownership has watered down the 'prestige pharmacy' positioning a bit. Still a reasonable pick for hydration-forward routines.
Pros
- ✓ Life Plankton has real research behind it
- ✓ Strong hydration-focused lineup
- ✓ Widely available globally
- ✓ Reasonable premium-pharmacy pricing
Cons
- ✗ Brand energy has dipped in 2020s
- ✗ Formulations less distinctive than they used to be
- ✗ Not really a pharmacy brand — sold mostly at Sephora/department stores
Rejuran
Rejuran is the consumer-skincare arm of Pharma Research Products, the Korean biopharma company that developed the original Rejuran Healer injectable — the same PDRN (polydeoxyribonucleotide) dermal treatment that's been a staple of Korean aesthetic clinics since 2014. The topical line translates that clinical DNA into daily-use products, anchored by the patented c-PDRN® complex at 0.5% concentration plus proprietary DOT® (Dermal Optimizing Technology) delivery. The Turnover Ampoule is the hero: a lightweight serum that targets fine lines, firmness, and texture with the same salmon-DNA active that made the injectable famous. Rejuran launched at Sephora US in 2024, won the 2025 Olive Young Slow Aging award, and has become the face of the PDRN trend that's dominating K-beauty in 2025–2026. The price point is premium-mid ($45–55), justified by the clinical pedigree and patented delivery system. Worth reaching for if you want the PDRN trend from the company that actually invented it.
Pros
- ✓ invented the PDRN category — the original, not a copycat
