Brand Comparison
ISDIN vs Mediheal
A head-to-head comparison of two popular K-beauty brands. Which one is right for your skin?
Our Pick
ISDIN
Larger product range
ISDIN
ISDIN is Spain's #1 dermatologist-recommended sunscreen brand and arguably the most clinically considered sunscreen house in the world. Founded in 1975 in Barcelona, the brand's R&D investment in photo-immunoprevention is unmatched: the Eryfotona Actinica line pairs broad-spectrum mineral SPF with photolyase enzymes (sourced from blue-green algae) that actively repair UV-induced DNA damage already in the skin — a mechanism no other major brand has commercialised. The Fusion Water Magic SPF 50 is the viral disappearing-finish daily, and the Flavo-C ampoules are the antioxidant ritual prescribed before vitamin C even became a Sephora category. ISDIN's identity is hospital-pedigree photoprotection translated into wearable, daily-driver formulations — the dermatologist's prescription pad in tube form.
Pros
- ✓ Eryfotona Actinica with photolyase DNA-repair — uniquely clinical photoprotection
- ✓ Fusion Water Magic — the viral water-feel daily SPF that disappears on contact
- ✓ single-dose Isdinceutics ampoule format — preserves vitamin C without oxidation
- ✓ the most-prescribed Spanish dermatology sunscreen brand globally
Cons
- ✗ premium pricing tier for what looks superficially like generic SPF
- ✗ branding feels clinical-functional, not editorial
- ✗ international distribution skews to pharmacy / medical channels — not Sephora-shelf
- ✗ Eryfotona Actinica's photolyase claim is supported by company data, not yet meta-analysis
Mediheal
Mediheal is the top-selling skincare brand at Olive Young for two years running — beating more than 3,000 brands. Their sheet masks created the modern sheet mask category, and their Madecassoside Blemish Pad saw 820% year-over-year growth. If you only add one new sheet mask brand to your routine, make it this one.
