Avene · F-Beauty
Best Avene Products for Acne-Prone Skin
5 Avene picks that actually work on acne-prone skin — ranked by editor rating, not by what the brand pushes hardest. Updated 2026.
The ultimate barrier repair brand — their thermal water is genuinely backed by clinical research.
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8.5/10 · serumCleanance Comedomed Anti-Blemish Concentrate
Clinically proven to reduce blemishes by 51% in 7 days — the French pharmacy acne treatment with real data behind it.
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8.5/10 · moisturizerCleanance Hydra Soothing Cream
Avène's specialist moisturizer for clients on harsh acne medications (isotretinoin, prescription tretinoin) where the barrier is fundamentally compromised. Combines Cicalfate's copper-zinc-sucralfate restoration with the Cleanance line's non-comedogenic discipline. The acne-meets-sensitive cream French dermatologists prescribe alongside Roaccutane.
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8.4/10 · sunscreenCleanance Sunscreen SPF 50+ Mattifying Fluid
Avène's oily-skin SPF — a rare French pharmacy sunscreen that's actually formulated for the skin type that needs it most. The protection system runs broad-spectrum chemical filters (Tinosorb S, Tinosorb M, Octocrylene, Uvinul A Plus) for SPF 50+ at UVA-PF 33+, paired with monolaurin (a natural sebum-regulating active) and silica powders for genuine matte hold. Niacinamide is layered in for tone-evening and additional sebum control. The fluid texture absorbs into a true matte finish — wearable as a primer under makeup. Fragrance-free. At $30 for 50ml, this is the value pick in the French sunscreen lineup for oily skin — comparable formulations from La Roche-Posay or Bioderma are $40+.
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8.3/10 · serumCleanance Comedomed Anti-Blemish Concentrate
Avène's Comedomed features Comedoclastin — a patented milk thistle extract that Pierre Fabre developed specifically to target comedones (the precursor to acne breakouts). Instead of treating existing acne, it prevents new comedones from forming. Under €22 in French pharmacies. The preventive approach to acne that French dermatology prefers over aggressive reactive treatments.
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8.2/10 · exfoliantCleanance AHA Exfoliating Serum
Triple acid exfoliant (AHA + PHA) with thermal water — the gentle French approach to chemical exfoliation.